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  Quarterly Shareholder Update: 02/24/2011
   
 
   
Ocular Blood Flow Analyzer (BFA)  
   
Paradigm’s Blood Flow Analyzer (BFA) is a tonometer that offers a fast clinically proven measurement of Ocular Blood flow (OBF), which is recognized as an important measurement in the detection and management of glaucoma and other retinal vascular disorders.  
   
Ocular Blood Flow Analyzer Features  
  • Early glaucoma detection before loss of visual field
  • Greater IOP measurement accuracy than traditional Goldmann tonometers
  • Accurate recording of IOP, Ocular Blood flow, Pulse Amplitude, and Systolic and Diastolic cycles
  • Measurement of IOP and Pulsatile Ocular Blood Flow by volume, not velocity
  • Fast and automatic testing
  • Complete 5 series of tests in 10 seconds
  • Concise patient data print outs
  • The ability to measure and quantify the effectiveness of glaucoma drug treatment regimens
  • Identify low and normal-tension glaucoma suspects
 
   
MALE EYES - Distribution of Ocular Blood Flow in male normals
( microlitres per minute )
 
   
   
   
   
   
 
 
   
   
   
   
   
   

1. Myopia - generally OBF readings for
myopes will show lower OBF values than
normals unless a correction is made for the
increase in eye size. These compensation
factors will be implemented in a future
release of the OBF Tonometer software.

2. Normal Tension Glaucoma's tend to have significantly lower OBFs than normals -a condition aggravated by a horizontal posture.

3. Some ocular and systemic drugs (e.g. those used to reduce high blood pressure) have the potential to substantially modify OBFs.

4. Symmetry - A large asymmetry in OBFs
(say 30% or more), combined with similar
IOPs and a low blood flow in one or both
eyes may indicate an external vascular
problem such as stenosis of the internal
carotid or ophthalmic arteries. This is even
more likely if the eye with the lower IOP has
the lower blood flow.
A large asymmetry in IOPs could account
for a matched asymmetry in OBFs however
such an asymmetry in IOPs is itself a
risk factor for Glaucoma.

 
 
 
 
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